Highlights at NBRC

Selected Publications - 2005

Belov L, Huang P, Chrisp JS, et al.
Screening microarrays of novel monoclonal antibodies for binding to T-, B- and myeloid leukaemia cells.
Immunol Methods. 2005 305:10-19.

Favoloro EJ, Bonar R, Aboud M et al.
How useful is the monitoring of (low molecular weight) heparin therapy by anti-Xa assay?
A laboratory perspective. Lab Hematol. 2005 11:157-62.

Flower RLP and Lin M.
Purification of RBC Agglutinating Antibodies by Affinity Chromatography on Peptides Representing Variant
MNS Antigens. Transfusion Medicine 2005 15, 78.

Kamhieh S, Bode L, Bolton W, et al.
Significant differences in the Borna Disease Virus p24 region between nucleotide sequences from humans
in Australia and reference European strains. Transfusion Medicine 2005 15, 73.

Liang H, Morel-Kopp M-C, Clemetson JM, et al.
A Common Ancestral Glycoprotein (GP) IX Gene Mutation (Asn45Ser) Occurring in European Families
from Australia and Northern Europe with Bernard-Soulier Syndrome (BSS).
Thromb Haemostasis, 2005 94:599-605.

Toopran S, Kamhieh S and Flower RLP.
Application of Molecular Genetic Techniques to Detection & Characterisation of Antibody to the Scianna
2 Polymorphism. Australian Journal of Medical Science 2005 27, 133.

Woolfson A, Stebbing J, Tom BD et al.
Conservation of a unique CD cell surface mosaic in clinically heterogeneous HIV-infected individuals.
Blood 2005 106(3):1003-7.

Selected Publications - 2006

M Aboud, C Roddie, CM Ward et al.
The laboratory diagnosis of lupus anticoagulant in patients on oral anticoagulation.
Clin Lab Haematol 2006 28:105-110.

Belov L, Mulligan SP, Barber N, et al.
Analysis of human leukemias and lymphomas using extensive immunophenotypes from an antibody microarray.
Br J Haematol 2006 135:184-197.

Flower RL and Ludwig H.
Presence of Borna disease virus (BDV)-specific structural components in human blood plasma.
J Clin Virol. 2006 36:309-311.

Greenwood MJ, Seftel MD, Richardson C, et al.
Leukocyte count as a predictor of death during remission induction in acute myeloid leukemia.
Leuk Lymphoma 2006 47:1245-52.

WS Stevenson, R Hoyt, H Kiu, et al.
Point mutations in MYB and the KIX domain of EP300 are uncommon in the human myeloproliferative disorders.
Blood 2006 107:1735.

WS Stevenson, R Hoyt, A Bell, et al.
Genetic heterogeneity of granulocytes for the JAK2 V617F mutation in essential thrombocythemia:
implications for mutation detection in peripheral blood. Pathology 2006, 38:336-42.

I Stewart, C Roddie, A Gill, et al.
Elevated serum FGF23 concentrations in plasma cell dyscrasias. Bone 2006 39: 369-76.

Taylor BA, Tofler GH, Carey HMR, et al.
Full mouth tooth extraction lowers systemic inflammatory and thrombotic markers of cardiovascular risk.
J Dental Research 2006 85:74-78.

S Wong, M-C Morel-Kopp, Q Chen, et al.
Overcoming Aspirin Resistance: Increased platelet inhibition with combination aspirin and clopidogrel
and high dose aspirin therapy in aspirin resistant patients with peripheral vascular disease.
Thromb Haemostasis 2006 95:1042-3.

S Wong, C Ward, M Appleberg, DR Lewis.
Point of care testing of aspirin resistance in patients with vascular disease.
ANZ J Surg 2006 76:873-877.

Selected Publications - 2007

Curnow JL, Morel-Kopp M-C, Roddie C, et al.
Reduced Fibrinolysis and Increased Fibrin Generation can be Detected in Hypercoagulable Patients Using
the Overall Haemostatic Potential Assay (OHP). J Thromb Haemost 2007 5:528-34.

Favaloro EJ, Bonar R, Duncan E, et al.
Mis-identification of factor inhibitors by diagnostic haemostasis laboratories: recognition of pitfalls
and elucidation of strategies. A follow up to a large multicentre evaluation. Pathology. 2007 39:504-11.

Johnston AM, Aboud M, Morel-Kopp MC, et al.
Use of a Functional Assay to Diagnose Protein S Deficiency; Increasing Testing of Obstetric Patients Yields
Unreliable Results. Internal Medical Journal 2007 37:409-11 BT.

B T Kile, AD Panopoulos, RA Stirzaker, et al.
Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia.
Blood 2007 110:2371-80.

Liang HPH, Morel-Kopp M-C, Curtin J, et al.
Heterozygous Loss of Platelet Glycoprotein (GP) Ib-V-IX Variably Affects Platelet Function in
Velocardiofacial Syndrome(VCFS) Patients. Thromb Haemost 2007; 98:1298-308.

The Van Gogh Investigators.
Idraparinux versus standard therapy for venous thromboembolic disease. New Engl J Med 2007 357:1094-1104.

The Van Gogh Investigators.
Extended prophylaxis of venous thromboembolism with idraparinux. New Engl J Med 2007 357:1105-1112.

White D, Saunders V, Grigg A et al.
Measurement of in vivo BCR-ABL kinase inhibition to monitor imatinib-induced target blockade and predict
response in chronic myeloid leukemia. J Clin Oncol 2007 25:4445-51.

Selected Publications - 2008/9

C Weir, M-C Morel-Kopp, A Gill, et al.
Mesenchymal stem cells: isolation, characterisation and in vivo fluorescent dye tracking.
Heart Lung Circulation 2008 17:395-403.

Tanaka R, Kuroda J, Stevenson W,et al.
Fully automated and super-rapid system for the detection of JAK2V617F mutation.
Leuk Res. 2008 32 (9):1462-7

AK Kakkar, B Brenner, O Dahl et al.
Extended duration rivaroxaban versus short-term enoxaparin for the prevention of venous
thromboembolism after total hip arthroplasty: a double-blind, randomised controlled trial.
Lancet 2008 published online June 25, 2008.

T Buckley, R Bartrop, S McKinley et al.
A Prospective Study Of Early Bereavement On Psychological And Behavioural Cardiac Risk Factors
Internal Medical Journal (in press 2008)

CA Hyland, G J Gardener, H Davies, M Ahvenainen, RL Flower, D Irwin, JM Morris,
CM Ward and JA Hyett.
Evaluation of non-invasive prenatal RHD genotyping of the fetus Med J Aust 2009; 191 (1): 21-25.

M-C Morel-Kopp, L McLean, Q Chen, et al.
The Association of Depression with Platelet Activation: Evidence for a Treatment Effect.
J Thromb Haemost (in press 2008)

Barber N, Gez S, Belov L, Mulligan SP, Woolfson A, Christopherson RI.
Profiling CD antigens on leukemias with an antibody microarray. FEBS Letters, 2009 583: 1785-1791

Tong WG, Wei Y, Stevenson W, et al.
Preclinical antileukemia activity of JNJ-26481585, a potent second-generation histone deacetylase inhibitor.
Leuk Res. 2009 (epub.Aug 12)

Postgraduate Completions

Awards and Honours for NBRC Staff

2002
Christopher Ward
Kanematsu Memorial Research Award, RCPA

2003
Vivien Chen
Presidential Award for best research presentation, ASBT

2005
Robert Flower
CSL Travelling Fellowship

2006
Jennifer Curnow
Australasian Society of Thrombosis and Haemostasis Medal - (Best Young Investigator)

Helena Liang
Young Investigator Award,4th Asia-Pacific Congress on Thrombosis and Haemostasis

William Stevenson
Kanematsu Memorial Research Award, RCPA

2007
Jennifer Curnow
Presidential Award (Best Research Paper)
...Australian and New Zealand Society of Blood Transfusion (ANZSBT)
Travel Grant, Australasian Society of Thrombosis and Haemostasis (ASTH)

Robert Flower
NBA Visiting Fellow to Indian Institute of Immunohaematology, Mumbai,
Visiting Professor, Transfusion Medicine Workshop, University of Malaya

William Stevenson
International Clinical and Research Fellowship 2007, Cancer Institute NSW

Christopher Ward
Elected President of the Australasian Society of Thrombosis and Haemostasis

2008
Christopher Ward
Australian Council Member, asia-Pacific Society of Thrombosis and Haemostasis

Brad McEwen
Astra-Zeneca Scholarship, RNSH

2009
Chee-Wee Tan
Australasian Society of Thrombosis and Haemostasis Medal -(Runner-Up)
Travel Grant, Australasian Society of Thrombosis and Haemostasis (ASTH)

Marie-Christine Morel-Kopp
Travel Grant, Australasian Society of Thrombosis and Haemostasis (ASTH)

Chee-Wee Tan
Douglas Piper Award, RNSH/UTS/USyd/KIMR Scientific Research Meeting